In a First, Scalable Production of Human Kidney Organoids Using Perfused Pig Kidneys

Breakthrough in Kidney Organoid Production

A novel technique has been developed, enabling the scalable production of human kidney organoids by integrating them into perfused pig kidneys.

This pioneering technology involves combining human kidney organoids with ex vivo pig kidneys, which can then be transplanted back into the same animal to assess their viability.

“Systematic production of human kidney organoids for transplantation in porcine kidneys during ex vivo machine perfusion.”

Published in Nature Biomedical Engineering, this research marks a significant milestone in regenerative and personalized medicine, paving the way for the use of kidney organoids derived from human stem cells in clinical trials.

Author's summary: Scalable kidney organoid production achieved.

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GEN - Genetic Engineering and Biotechnology News GEN - Genetic Engineering and Biotechnology News — 2025-11-01

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