Heart Health: Long-Term Melatonin Use Linked to Cardiovascular Risk
New research indicates that individuals with insomnia who take melatonin supplements for over a year may face an increased risk of heart failure compared to those who do not use this sleep aid. The study found that long-term melatonin users were more likely to be diagnosed with heart failure, hospitalized for the condition, or die from any cause.
Study Presentation and Limitations
This preliminary research will be presented at the American Heart Association’s Scientific Sessions 2025 in New Orleans but has not yet been published in a peer-reviewed journal. The researchers emphasized that their findings do not prove a direct cause-and-effect link between melatonin use and heart failure risk.
Safety Concerns and Recommendations
Despite the lack of definitive causality, the results raise important safety questions about prolonged melatonin use, suggesting the need for additional studies to evaluate its cardiovascular effects.
- Many melatonin supplements are available over-the-counter without prescriptions.
- These products are not strictly regulated.
- People often use melatonin without medical supervision.
“Melatonin supplements may not be as harmless as commonly assumed.”
Researchers highlight the importance of further research to ensure the cardiovascular safety of melatonin supplements.
Author's summary: Long-term melatonin supplementation may increase heart failure risk, urging caution and further research on its cardiovascular safety due to the lack of regulation and guidance.